Patents

PATENTS – APPLIED AND/OR GRANTED:

Single dose pharmacokinetics of Tobramycin after administration of a novel dry powder formulation (TPI) in subjects with Cystic Fibrosis (CF). Filed ~ Oct 6, 2004

Method of therapeutic administration of DHE to enable rapid relief of migraine while minimizing side effect profile. US Patents 7,994,197 B2 Issued Aug 9, 2011;  US Patent 8,119,639 Issued Feb 21, 2012; US Patent 8,148,377 Issued April 3, 2012; European patent 2112/2425820 Issued March 27, 2012

Inhaled statin plus ICS in combination for atherogenic/inflammatory CAD. Filed ~ April, 2008

PK profile of inhaled DHE. Filed ~ April, 2008

Method for administering corticosteroid formulations. Filed 10 November  2008; Granted 14 May 2009  WO 2009/062193 A3

Nebulized delivery of sub-micron budesonide particles. Applied for ~ April, 2008

Inhaled delivery of TGFβ3 for treatment of IPF. Filed ~ April, 2008

Formoterol  budesonide combination particles delivered via the Tempo inhaler. Filed May 15, 2009          MROI     83PROV

Intrapulmonary administration of dihydroergotamine to mammals. Filed June 26,    2009                         MROI     83PROV

Inhaled Statins – Delivery methods and devices for treating inflammatory and fibrotic lung disorders.  Filed May 3, 2009       MROI  006 PROV  # 40,346
Final Filed April 30, 2010         MROI  006  # 12/799,737

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